Optimizing Deep Brain Stimulation

Optimizing deep-brain-stimulation signals used in Parkinson disease by using the cloud, AI and mathematical modeling of symptoms, and MRI/CT images.

Deep-brain stimulation (DBS) is one of the most effective treatments of the symptoms of Parkinson disease, including tremor. However, the various parameters of the DBS signal is rarely optimized, and often needs adjustments from a highly skilled neurologist. It seldom achieves maximum effect.

Project AI-TRUST is our joint-venture project with Uppsala University and Uppsala University Hospital. It is a cloud- and AI-powered digital health platform developed to increase the effectiveness Parkinson care. The platform will e.g., give hospital personal access to AI-powered parameter suggestions by using various sources of inputs including pre- and post-op brain images and symptom quantification indicators.

Overview of a DBS-system. Image credit

Head of the research group that takes care of all modelling and algorithms development Prof. Alexander Medvedev from control systems group at Uppsala university. The neurological expert and manager of the clinical trials is Assoc. Prof. Dag Nyholm from the Uppsala University Hospital. Stardots is taking care of all application development, cloud services and AI integrations.

DBS-probes shown in X-ray of the skull. Image credit: Hellerhoff, Used under CC BY-SA 3.0 license Image has been cropped

Stardots is thrilled to have three extremely competent and hardworking project partners and are looking forward to improving DBS-treatment and hence the quality of life of patients with Parkinson´s disease. In addition, Stardots was awarded an AI grant from Vinnova, Swedish Agency for Innovation.

sPark is a symptom quantifier for neurological diseases such as Parkinson and is developed together with Uppsala university.

More information about AI-TRUST will follow, but please do not hesitate to contact Stardots at info@stardots.se

For an example of how effective DBS may be, see this Youtube video: https://www.youtube.com/watch?v=uBh2LxTW0s0